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Mary Jane Burgers & Brew

Hamburger restaurant · $10 to $20 ·

102 N Jackson St, Perryville, MO 63775, United States

Menu and hours last checked

Mary Jane Burgers & Brew

About Mary Jane Burgers & Brew

Located at 102 N Jackson St in Perryville, MO, Mary Jane Burgers & Brew is a vibrant, casual burger joint that offers much more than just your average meal. Whether you're looking to sit outside, grab a quick bite to go, or enjoy a relaxed meal inside, this place has something for everyone. With service options like outdoor seating, dine-in, takeaway, and delivery, it’s perfect for any occasion-whether you're out for a casual hangout or just need a tasty comfort food fix.

The restaurant specializes in juicy, mouth-watering burgers, but that's just the start. They also serve a variety of comfort food options, including vegetarian choices, so there's something for all tastes. For those who like to unwind with a drink, Mary Jane Burgers & Brew offers a great selection of alcohol, from craft beer and wine to cocktails and spirits. The happy hour here is always a hit, with food and drinks available at discounted prices.

If you're in the mood for something late-night, no worries-the restaurant serves up satisfying late-night food options, making it the perfect spot to grab a snack after a night out. Plus, they offer small plates for those who like to try a little bit of everything. And if you're just looking for a quick bite or need some fuel to get you through the day, you'll find plenty of quick and satisfying options to keep you going.

Overall, Mary Jane Burgers & Brew is more than just a place to grab a burger; it's a local hotspot with a great atmosphere, a fantastic drink selection, and a menu that caters to all cravings. Whether you're a meat-lover, vegetarian, or just in the mood for a cold beer with a tasty bite, this restaurant has you covered.

Where this information comes from

Prices and dish names are transcribed from the restaurant's printed menu, photographed in August 2026 and reproduced on the menu page. Hours, address and service options come from the restaurant's public business profile. An editor confirmed the restaurant was trading on 4 September 2026. Something wrong? Tell us.

Photos

Business info

From the business

  • Identifies as women-owned

Service options

  • Outdoor seating
  • Takeaway
  • Dine-in
  • Delivery

Highlights

  • Fast service
  • Great beer selection
  • Great cocktails
  • Great wine list
  • Live music
  • Serves local specialty
  • Sport

Popular for

  • Lunch
  • Dinner
  • Solo dining

Accessibility

  • Wheelchair-accessible car park
  • Wheelchair-accessible entrance
  • Wheelchair-accessible seating
  • Wheelchair-accessible toilet

Offerings

  • Alcohol
  • Beer
  • Cocktails
  • Coffee
  • Comfort food
  • Happy-hour drinks
  • Happy-hour food
  • Late-night food
  • Quick bite
  • Small plates
  • Spirits
  • Vegetarian options
  • Wine

Dining options

  • Brunch
  • Lunch
  • Dinner
  • Catering
  • Dessert
  • Seating
  • Table service

Amenities

  • Bar on site
  • Toilet
  • Wi-Fi
  • Wi-Fi

Atmosphere

  • Casual
  • Cosy
  • Historic
  • Trendy

Crowd

  • Family friendly
  • Groups
  • LGBTQ+ friendly
  • Tourists
  • University students

Planning

  • Accepts reservations

Payments

  • Credit cards
  • Debit cards
  • NFC mobile payments

Children

  • Good for kids
  • High chairs
  • Kids' menu

Parking

  • Free of charge street parking
  • Free parking lot
  • Parking

Pets

  • Dogs allowed outside

Opening hours

  • Monday 11:00 AM - 09:00 PM
  • Tuesday 11:00 AM - 09:00 PM
  • Wednesday 11:00 AM - 09:00 PM
  • Thursday 11:00 AM - 09:00 PM
  • Friday 11:00 AM - 10:00 PM
  • Saturday 10:00 AM - 10:00 PM
  • Sunday 10:00 AM - 08:00 PM

Hours can change on public holidays. Call ahead if you are making a special trip.

Location

102 N Jackson St, Perryville, MO 63775, United States

Diner notes

4.7 4.7 out of 5 · 2903 notes
  • 5 stars 2423
  • 4 stars 386
  • 3 stars 106
  • 2 stars 57
  • 1 stars 53
5 out of 5
Traveling down I-55, then stop at Mary Janes! You won't be disappointed. We stopped to have lunch here nearly every time we travel between MS and St. Louis. The food, service, and atmosphere are all awesome. We typically get some sort of burger or sandwich with fries or sweet potato fries. These are not your run of the mill burgers either . . . they are chef created. They also support local farms and businesses. Many of the buns are baked fresh at Hoeckels Bakery. Oh, and be sure to try the maple aoli with your sweet potato fries. Yum! Lexi has been our server the last 2 visits and is just awesome . . . attentive and sweet. We love Mary Jane's in Perryville, MO!
TK Tracy Kirkley, Real Estate Professional Ate here , 17:43 am
5 out of 5
Absolutely delicious good in a super cute environment. They have a vegetarian impossible burger and a grain/bean vegetarian burger. The grain/bean was one of the best vegetarian burgers I have ever had. An added bonus was the unlimited fries! The service was also great! Highly recommend.
E Emily Ate here , 17:43 am
5 out of 5
Mary Jane Burger and Brew in Perryville, MO, is a delightful culinary gem! The moment you step in, the inviting atmosphere sets the stage for an exceptional dining experience. Their burgers are a standout, featuring juicy patties and creative toppings that cater to all tastes. The fries are perfectly crispy, and the selection of local brews complements the meal beautifully. The staff is friendly and attentive, making you feel right at home. Whether you're a local or just passing through, Mary Jane's is a must-visit!
MR Mike Rohan Ate here , 17:43 am

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